Two Phase 3 trials failed because they measured PC pain at the wrong frequency.
Pachyonychia Congenita pain fluctuates daily with weight-bearing, footwear, terrain, and sweat exposure — yet the two most advanced clinical trials failed because their primary endpoint captured only periodic clinic-visit snapshots. The pain that keeps patients crawling to the bathroom at night and the trimming sessions that go too deep are the data the field needs. Forma captures this daily signal.
Forecast
Based on prior Topics logging
Topics
How it works
15 seconds of speech. 25 data points.
Forma turns each patient into a continuous data stream. By voice or text, patients log daily pain intensity and type, plantar skin events, footwear and terrain triggers, trimming sessions with tool and outcome detail, and weekly quality-of-life impact in under a minute. No forms, no recall bias. The result is a structured, longitudinal dataset across every PC domain — daily pain trajectories disaggregated by pressure vs. burning vs. blister pain, trimming frequency correlated with pain relief or complication, and trigger patterns (concrete, heat, sweaty shoes) visible across weeks rather than remembered at a visit.
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Forecast
Based on prior Topics logging
Topics
Structured, coded, longitudinal
- Timing
- Time of onset:This morningShower duration:15 min
- Location
- Crack location:Feet
- Severity
- Crack count:3 newCrack status:New onsetPain severity:Extreme
- Actions
- Cream applied:Vanicream
- Environmental
- Humidity:34%Temperature:72°FAir quality (AQI):42 — Good
- Outcome
- Pain outcome:Significantly decreasedTreatment response:Positive
See Pachyonychia Congenita configured for your study
See Forma configured for Pachyonychia Congenita