DermatologyRare Genetic Skin Fragility

Epidermolysis Bullosa

Voice-first health observation platform for Epidermolysis Bullosa, capturing wound status, pain, itch, nutrition, treatment response, and quality of life through natural language.

Study Overview

About this study

Epidermolysis Bullosa encompasses a group of rare inherited skin fragility disorders where trivial mechanical trauma causes blistering, creating a daily burden of wound care, pain management, and nutritional support that is largely invisible to clinicians between visits. Forma Health captures continuous patient-reported data across all EB clinical domains — wound trajectory, multi-dimensional pain, itch severity, treatment response to gene therapies, nutritional status, hand function decline, and cancer surveillance — through voice-first natural language input designed for patients with severe hand dysfunction. This longitudinal data fills the gap between clinic-based assessments and cross-sectional registry surveys, serving both clinical care and the urgent real-world evidence needs of the rapidly expanding EB therapeutic landscape.

What's included

Key features

  • Voice-first wound status logging with daily blister count and healing trajectory tracking
  • Multi-dimensional pain capture separating background, procedural, and breakthrough pain
  • Gene therapy and wound treatment response tracking per treated wound (Vyjuvek, Filsuvez)
  • Itch severity monitoring with scratch-damage impact tracking
  • Bandage change session logging with duration, product, and complication capture
  • Nutritional intake and swallowing difficulty assessment with weight tracking
  • Pseudosyndactyly and hand function progression monitoring
  • Cancer surveillance flagging for non-healing wounds and biopsy tracking

Topic Configuration

Configured topics

Each study includes pre-configured topics that patients interact with daily. Here are examples of how we've set up data collection for this study.

Wound Status

Sample questions

  • How many active wounds today?
  • Any new blisters?
  • Are wounds improving or worsening?
  • Which body regions are affected?

Pain

Sample questions

  • What is your background pain level (0-10)?
  • How bad was bandage change pain?
  • Any breakthrough pain episodes?

Treatment Application

Sample questions

  • Which treatment was applied?
  • Which wounds were treated?
  • How are treated wounds responding?

Itch / Pruritus

Sample questions

  • How severe is the itch (0-10)?
  • Where is the itch worst?
  • Any skin damage from scratching?

Wound Care Session

Sample questions

  • How long did the bandage change take?
  • Which products were used?
  • Any complications during the change?

Ready to see Epidermolysis Bullosa in action?

Book a demo and we'll walk you through this study configuration live.